Scientist / Senior Scientist

Molecular and Cellular Neuroscience 
NeuCyte, Inc. – Mountain View, CA

Contact info: careers@neucytelabs.com

Who we are:

NeuCyte is an early stage biotechnology company that focuses on developing treatments for those suffering from neurological and neurodegenerative disorders. We develop translatable cell-based assays for modelling neuro related disorders using patient-derived and genetically-engineered neural cell types to discover novel therapeutics. Based on our SynFire® technology, our proprietary human neural in vitro platforms assess complex electrophysiological and

morphological readouts suited for target identification and validation, as well as drug efficacy testing. NeuCyte Laboratories is the product and service division of NeuCyte.

What we're looking for: 

NeuCyte is seeking a highly motivated Scientist / Senior Scientist to join our stem cell technology team. In this role, the successful candidate will provide molecular and cellular neuroscience expertise to the development of human cellular model systems for drug discovery. The position requires strong background in in vitro disease modeling and phenotypic assay development.


What you’ll do:

  • Provide NeuCyte's disease programs with molecular and cellular tools for phenotypic drug screening

  • Participate in/Lead the design and implementation of cell-based assays 

  • Participate in the design and management of an iPSC work environment including QA and QC

  • Develop and perform high-content imaging assays for phenotypic drug screening with expertise in Operetta and IncuCyte imaging platforms preferred; develop automated image analysis pipelines; support the general needs around imaging and microscopy

  • Work with the team to develop and perform molecular biology and biochemistry assays for phenotypic drug screening, develop data analysis pipelines, and support the general needs around molecular biology and biochemistry

  • Work with the team to maintain molecular biology and imaging-related instruments, interact with service partners and instrument manufacturers

  • Participate in/Lead preparation and maintenance of cell cultures for molecular biology, high-content imaging, and functional assays 

  • Work with the team to define and implement procedures for data management 

  • Keep up with the technology field, review relevant literature, and evaluate systems and analysis solutions

  • Prepare SOPs and train/supervise technical staff to assist with assays as needed

  • Write project reports, present projects at internal and external meetings 

Required: 

  • PhD with 3-5 years of relevant technical experience, preferably in a pharmaceutical or biotech lab environment 

  • Experience with phenotypic assays and related data interpretation

  • Experience with molecular biology and biochemistry assays such as DNA and RNA extraction, PCR and qPCR, plasmid construction, Western blotting, ELISA, etc.

  • Proficiency in the use of at least one commercial imaging system and related data analysis software

  • Deep expertise in microscopy and imaging technologies, instrument handling, and trouble-shooting

  • Basic knowledge in genomics

  • Clear written and oral communication and detailed documentation skills​

Preferred:

  • Background in neuroscience

  • Deep knowledge in molecular and cellular biology

  • Experience with iPSC culture maintenance

  • Basic computer programming skills for data processing​

 

Compensation:

  • Competitive salary and benefits

NeuCyte is proud to be an Equal Opportunity Employer and is committed to providing an environment of mutual respect and celebrating diversity.