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Posters

Development of iPSC-derived Pre-clinical Drug Screening Assays for KIF1A Associated Neurological Disorder

A Murchison 1, M Nicholson 1, P Zhou 1, D Verden 2, D Lessard 2, and W Poon 1

1 NeuCyte Inc CA; 2 KIF1A ORG, NY

Miniaturized Isogenic iPSC-derived 3D NeuroImmune Assembloids for High-throughput Drug Screening

M Nicholson 1, A Murchison 1, N Salinas 2, P Zhou 1, M Strain 3, J Whalen 3, D Stearns 3, A Deng 1, D Lessard 4, T Huang 1, B Fathollahi 3, E Ullian 2, and W Poon 1

1 NeuCyte, Inc., CA; 2 Department of Ophthalmology, UCSF, CA; 3 Acoustic-Bio, CA; 4 KIF1A.ORG, NY

Added in 2022

Development of Multi-Electrode Array (MEA) Assay for Phenotypic Drug Screening

J Kammonen, S Williams, L Butler, D Magnani, J Anton, C Mansat-Bhattacharyya, G Gulbahce, R Burley, O Fedorenko, M Iovino, Charles River, UK

Added in 2022

Development of iPSC-derived Alzheimer Disease (AD) platforms for phenotypic screening

A Murchison, P Zhou, C Noel, D Haag, J Wu, T Huang, and W Poon, NeuCyte, Inc., CA

Characterization of an in vitro synaptic propagation assay using iPSC-derived neurons and multiwell microelectrode array technology

D Millard, D Sullivan, H Hayes, Axion BioSystems, GA

The electrophysiological responses to antibacterial drug in human iPSC-derived neurons demonstrate the claissification of antibacterial drugs encephalopathy in clinical

Y Ishinashi, K Ogawa, and I Suzuki, Tohoku Institute of Technology, Japan

Establishing an In Vitro Assay for Predicting Neurotoxicity Risks Using Functional Human iPSC-Derived Neurons

H Liu, W Zhong, L Saavedra, T Portmann, J Davila, D Haag, and T Huang, NeuCyte Inc., CA

In Vitro Neurotoxicity Testing Using Functional Human iPSC-Derived Neurons

H Liu1, L Saavedra1, K Wallace2, T Freudenrich2, T Portmann1, J Davila1, TJ Shafer2, M Wernig3, and D Haag1

1 NeuCyte Inc., CA, 2 US EPA, 3 Stanford University, CA

Development of a Fully Defined, Synaptically Competent iPSC-Derived Neuronal Platform for Drug Discovery

L Saavedra, V Dang, A Fua, and J Davila, and D Haag, NeuCyte Inc., CA

New iPSC-Based Neural In Vitro Approach for Seizure Liability Testing

L Saavedra, A Fua, V Dang, J Davila, and D Haag, NeuCyte Inc., CA

Comparison of Acute Effects of Neurotoxic Compounds in Neural Networks from Rodent and Human Neurons Using Microelectrode Arrays

T Freudenrich1, K Wallace1, D Haag2, L Saavedra2, M Mall2 , WR Mundy1, J Davila2, TC Südhof3, M Wernig2, and TJ Shafer1
1 US EPA; 2 Stanford University, CA

Application of Patient Generated iPSCs-Derived Neurons to Define the Pathophysiology of FXS Neurons

S Botelho , L Saavedra, A Fua, T Huang, J Dávila, D Haag, V Dang, NeuCyte Inc., CA

Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures

L Saavedra2,4, K Wallace1, T Freudenrich1, M Mall2, W Mundy1, J Davila2,4, T Südhof3, T Shafer1, M Wernig2, and D Haag2,4
1US EPA; 2 Stanford University, CA; 3 Stanford University, CA; 4 NeuCyte Inc., CA