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Development of iPSC-derived Pre-clinical Drug Screening Assays for KIF1A Associated Neurological Disorder

      A Murchison 1, M Nicholson 1, P Zhou 1, D Verden 2, D Lessard 2, and W Poon 1

       1 NeuCyte Inc CA; 2 KIF1A ORG, NY

Miniaturized Isogenic iPSC-derived 3D NeuroImmune Assembloids for High-throughput Drug Scr

Miniaturized Isogenic iPSC-derived 3D NeuroImmune Assembloids for High-throughput Drug Screening

      M Nicholson 1, A Murchison 1, N Salinas 2, P Zhou 1, M Strain 3, J Whalen 3, D Stearns 3, A Deng 1,                   D Lessard 4, T Huang 1, B Fathollahi 3, E Ullian 2, and W Poon 1

       1 NeuCyte, Inc., CA; 2 Department of Ophthalmology, UCSF, CA; Acoustic-Bio, CA; KIF1A.ORG, NY

Development of Multi-Electrode Array (MEA) Assay for Phenotypic Drug Screening

      J Kammonen, S Williams, L Butler, D Magnani,  J Anton, C Mansat-Bhattacharyya, G Gulbahce, R Burley,          O Fedorenko, M Iovino, Charles River, UK

Development of iPSC-derived Alzheimer Disease (AD) platforms for phenotypic screening

Development of iPSC-derived Alzheimer Disease (AD) platforms for phenotypic screening

      A Murchison, P Zhou, C Noel, D Haag, J Wu, T Huang, and W Poon, NeuCyte, Inc., CA

Establishing an In Vitro Assay for Predicting Neurotoxicity Risks Using Functional Human i

Establishing an In Vitro Assay for Predicting Neurotoxicity Risks Using Functional Human iPSC-Derived Neurons

      H Liu, W Zhong, L Saavedra, T Portmann, J Davila, D Haag, and T Huang, NeuCyte Inc., CA

In Vitro Neurotoxicity Testing Using Functional Human iPSC-Derived Neurons

In Vitro Neurotoxicity Testing Using Functional Human iPSC-Derived Neurons

      H Liu1, L Saavedra1, K Wallace2, T Freudenrich2, T Portmann1, J Davila1, TJ Shafer2, M Wernig3, and D Haag1 

       1 NeuCyte Inc., CA, 2 US EPA, 3 Stanford University, CA

New iPSC-Based Neural In Vitro Approach for Seizure Liability Testing

New iPSC-Based Neural In Vitro Approach for Seizure Liability Testing

      L Saavedra, A Fua, V Dang, J Davila, and D Haag, NeuCyte Inc., CA

Comparison of acute effects of neurotoxic compounds in neural networks from rodent and hum

Comparison of Acute Effects of Neurotoxic Compounds in Neural Networks from Rodent and Human Neurons Using Microelectrode Arrays

      T Freudenrich1, K Wallace1, D Haag2, L Saavedra2, M Mall2 , WR Mundy1, J Davila2, TC Südhof3, M Wernig2,           and TJ Shafer1
      1 US EPA; 2 Stanford University, CA

Application of patient generated iPSCs derived neurons to define the pathophysiology of FX

Application of Patient Generated iPSCs-Derived Neurons to Define the Pathophysiology of FXS Neurons

      S Botelho , L Saavedra, A Fua, T Huang, J Dávila, D Haag, V Dang, NeuCyte Inc., CA

Application of patient generated iPSCs derived neurons to define the pathophysiology of FX

Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures

      L Saavedra2,4, K Wallace1, T Freudenrich1, M Mall2, W Mundy1, J Davila2,4, T Südhof3, T Shafer1, M Wernig2,           and D Haag2,4
      1US EPA; Stanford University, CA; 3 Stanford University, CA; NeuCyte Inc., CA

Functional Characterization of Neural Network Activity in Human iPSC-Derived Neuron/Glial

Functional Characterization of Neural Network Activity in Human iPSC-Derived Neuron/Glial Co-cultures

      T Molla, C Lee, P Zhou, W Zhong, L Saavedra, J Dávila and D Haag,  NeuCyte Inc., CA

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