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Yuto ISHIBASHI, Kazutoshi OGAWA, and Ikuro SUZUKI, Tohoku Institute of Technology, Japan
H Liu, W Zhong, L Saavedra, T Portmann, J Davila, D Haag, and T Huang, NeuCyte Inc., CA
In Vitro Neurotoxicity Testing Using Functional Human iPSC-Derived Neurons
H Liu1, L Saavedra1, K Wallace2, T Freudenrich2, T Portmann1, J Davila1, TJ Shafer2, M Wernig3, and D Haag1
1 NeuCyte Inc., CA, 2 US EPA, 3 Stanford University, CA
L Saavedra, Vu Cao Dang, A Fua, and J Davila, and D Haag, NeuCyte Inc., CA
New iPSC-Based Neural In Vitro Approach for Seizure Liability Testing
L Saavedra, A Fua, V Dang, J Davila, and D Haag, NeuCyte, CA
T Freudenrich1, K Wallace1, D Haag2, L Saavedra2, M Mall2 , WR Mundy1, J Davila2, TC Südhof3, M Wernig2, and TJ Shafer1
1 US EPA, 2 Stanford University, CA
Application of Patient Generated iPSCs-Derived Neurons to Define the Pathophysiology of FXS Neurons
S Botelho , L Saavedra, A Fua, T.Huang, J Dávila, D Haag, V Dang, NeuCyte, CA
L Saavedra2,4, K Wallace1, T Freudenrich1, M Mall2, WR Mundy1, J Davila2,4, TC Südhof3, TJ Shafer1, M Wernig2, and D Haag2,4
1US EPA, 2 Stanford University, CA, 3 Stanford University, CA, 4 NeuCyte, CA
T Molla, C Lee, P Zhou, W Zhong, L Saavedra, J Dávila and D Haag, NeuCyte, CA
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Publications on or with Our Core Technology
6. Pak, C. et al. Human Neuropsychiatric Disease Modeling using Conditional Deletion Reveals Synaptic Transmission Defects Caused by Heterozygous Mutations in NRXN1. Cell Stem Cell, 17(3): 316-28, 2015.
7. Yi, F. et al. Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons. Science, 352(6286): aaf2669, 2016.