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With the advantages of the SynFire® technology, such as rapid maturation and synaptic competence, our human neural in vitro platforms are uniquely suited for assessing relevant complex electrophysiology readouts, which allows better prediction of drug efficacy and potential CNS safety/toxicology than other systems.

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Powerful System for CNS Drug Discovery and Safety/Neurotoxicity Assessment 

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Here are the lab services we offer:

Custom iPSC-derived neuron production

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Custom assay performance

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In vitro neurotoxicity assessment

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Cell viability and apoptosis assays
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Autophagy and mitochondrial dysfunction assays
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Neural network activity testing
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Seizure liability testing
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Neurite outgrowth and morphology assessment
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Gene expression analysis

Our goal is to develop applications, assays and protocols to support clients’ needs using our technology platform. We always start with the questions you are trying to answer. We have the suitable infrastructure to support drug discovery and nonclinical safety assessment from low to high throughput based on the needs of the individual project.

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If you’re interested in our unique drug discovery and phenotypic screening capabilities, please contact us with your inquiry.