With the advantages of the SynFire® technology, such as rapid maturation and synaptic competence, our human neural in vitro platforms are uniquely suited for assessing relevant complex electrophysiology readouts, which allows better prediction of drug efficacy and potential CNS safety/toxicology than other systems.

Powerful System for CNS Drug Discovery and Safety/Neurotoxicity Assessment 

Here are the lab services we offer:

Custom iPSC-derived neuron production

Custom assay performance

In vitro neurotoxicity assessment

Cell viability and apoptosis assays
Autophagy and mitochondrial dysfunction assays
Neural network activity testing
Seizure liability testing
Neurite outgrowth and morphology assessment
Gene expression analysis

Our goal is to develop applications, assays and protocols to support clients’ needs using our technology platform. We always start with the questions you are trying to answer. We have the suitable infrastructure to support drug discovery and nonclinical safety assessment from low to high throughput based on the needs of the individual project.

If you’re interested in our unique drug discovery and phenotypic screening capabilities, please contact us with your inquiry.